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"Traditional Chinese Medicine Dictionary": Sophora japonica

Herbs name Sophora japonica

Pinyin HuáiHuā

Alias ​​Huai Rui ("Materia Medica").

Source "IWC Materia Medica"

Source for the leguminous plant Huai flowers or buds. Summer, flowers early open harvest flowers, goods called "Sophora japonica"; flowers are not mining flowers buds, goods called "Huai rice." Remove the impurities, dry day.

Original Huai ("Ya"), also known as: Sophora japonica, white Huai, fine leaf Huai, gold medicine tree, nursing tree.

Deciduous trees, up to 25 meters. Bark gray or dark gray, rough longitudinal crack. Dark yellow skin, stinky; branches brown, young when young, with hair, lenticels obvious. Leaves 7 to 15, ovate-oblong-ovate-lanceolate, 2.5 to 5 cm long, 1.5 to 2.6 cm wide, apex acuminate, base rounded Shaped or broadly cuneate, entire, above green, slightly bright, below creature white short hair; petiole length 2.5 mm; stipules sickle-like, caducous Spikelets terminal; flowers white, 1.5 cm long; calyx bell-shaped, 5-lobed; corolla butterfly, flagpoles concentric, with short claws, veins purple; stamens 10, unequal length; There are fine hairy, style curved pods long 2.5 ~ 5 cm, section, was bead-like, glabrous, green, fleshy, no cracking, very thin between the seeds. Seeds 1 ~ 6 capsules, dark brown, reniform. Flowering 7 to 8 months of fruit 10 to 11 months.

The ecological branch was born on a hillside, plain or planted in a garden. Most parts of our country are distributed. And Hebei, Shandong, Henan, Jiangsu, Guangdong, Guangxi, Liaoning and other places mainly producing areas.

Traits:

① Sophora japonica

Dry flowers, petals mostly scattered, complete flower like birds, about 1.5 cm in diameter, 5 petals, yellow or light brown, wrinkled, curly. Basal calyx tube yellow-green, apex 5-lobed. Stamens pale yellow, whiskers, sometimes curved. Ovary enlargement. Light, weak, slightly bitter taste. Color yellow and white, neat, no branches of impurities are better.

② Huai rice

Also known as: Sophora japonica ("Medical Yi Jane"). Department of dry buds, oval or long oval, 2.5 ~ 5 mm wide 1.5 ~ 2 mm appearance of yellowish brown or yellowish green, slightly shrinking, the lower part of the bell-shaped calyx, apex with obvious 5 teeth crack, sometimes There are short handles, the upper part is not open corolla, different sizes, calyx and corolla outside are sparsely white pubescent. , Taste slightly bitter. To buds strong, calyx green and thick, no branches are better.

Chemical composition containing rutin, buds in the content of more open after the content of less. And from the dried buds were triterpenoid saponin 0.4%, after hydrolysis of betulin, Huaihua diol and glucose, glucuronic acid.

(14%), B (1.25%) and propane (0.35%), and flavonoids different from rutin are flavonoids, Quality, Sophora japonica with 0.66%, Sophora japonica tannin content of about 4 times the raw Sophora japonica.

Pharmacological effects of:

① on the impact of capillaries

Sophora japonica in the composition of rutin and its aglycone quercetin can maintain the normal resistance of capillaries, reduce vascular permeability, can increase the brittleness of the capillaries to return to normal elasticity, quercetin can enhance the guinea pig , The resistance of the rat skin capillaries (with negative pressure caused by normal and heparinized animal skin petechia method), reduce vascular permeability (with rabbit-chloroform method), its role in capillary stability than Ruthering Glycosides strong 1/3. In recent years, quinone and other flavonoid alcohol compounds have been reported to inhibit the art of Alterus (subcutaneous injection of antigen, causing local edema and necrosis). Flavonoids in flavonoids have a biphasic effect on guinea pig and human enhanced capillary resistance: early temporary increase in capillary resistance, followed by strong and prolonged effects for several days, but The resistance of other flavonoids to capillaries is only a single phase effect. Continuous use of a large number of rutin and quercetin, can prevent the decompression caused by the rat lung bleeding.

② anti-inflammatory effect

Rutin and quercetin have a significant inhibitory effect on rutus in rats due to histamine, egg white, serotonin, formaldehyde, polyvinylpyrrolone-induced paw edema, and irritability caused by hyaluronidase Rat traumatic edema, and can prevent the development of conjunctivitis, auricular inflammation, pulmonary edema, the rabbit due to mustard oil caused by conjunctival edema, only mild inhibition, such as rutin dissolved in propylene glycol, the effect of prevention of inflammation better. Intravenous administration of rutin can inhibit the skin caused by rabbits serum, joint allergic inflammation and Arthus phenomenon, which may be from the capillaries of the wall has a protective effect, so that the capillary dense, inhibition of exudation caused by ruthen nitric acid ester Sodium salt can accelerate the recovery of thrombophlebitis in the hind limbs caused by the injection of turpentine. On the rutinoid flavonoid antigen principle, say a lot, such as excitement of the adrenal cortex (given rutin derivative, the adrenal glands in the vitamin C and cholesterol levels decreased, plasma sterols increased significantly), increased blood adrenaline (may Is due to catecholaminoxymethyltransferase or monoamine oxidase produced competitive inhibition), indirectly inhibited the permeability of capillaries, and the anterior vascular sphincter tension increased, reducing the total amount of true capillaries; Inhibition of hyaluronidase caused by; also considered to be protected by the mast cells of the "cleavage" and "threshing", thus inhibiting the release of proinflammatory amines, and hinder adrenaline decomposition caused by two factors. From the biochemical aspects that is because it blocked a variety of enzymes thiol, and with the enzyme in the main metal ions and the performance of anti-inflammatory effect. With regard to its anti-edema effect, it is considered to be due to the increase in the viscosity of hyaluronic acid, and inhibition of cell membrane adenosine triphosphatase

③ antispasmodic, anti-ulcer effect

Quercetin can reduce the tension of intestinal and bronchial smooth muscle, and its antispasmodic effect is 5 times stronger than that of rutin. X-ray studies show that rutin can decrease the gastric motility of rats and release the small intestine smooth muscle caused by barium chloride Spasm, the effectiveness of only Klein 1/14, subcutaneous injection of rutin 5 ~ 10 mg / kg, can significantly reduce the number of gastric ulcer lesions caused by ligation of pylorus, the effectiveness of reflex gastric ulcer than Kailing Qiang The Sophora japonica solution (containing rutinosine little) into the rabbit intestine, can stimulate the intestinal mucosa to increase the exudate.

④ on the cardiovascular system

Huai liquid on the frog heart has a slight excitement, the heart conduction system has a blocking effect. Rutin, quercetin, quercetin can also increase in vitro and in vitro frog heart contraction force and output, and reduce heart rate. Rutin to make the toads of the lower limbs and rabbits. Quercetin can expand coronary blood vessels and improve myocardial circulation. Sophora japonica 400 mg / kg for three days, can increase the mouse coronary blood flow more than a lot more and more much more and more much more and more much more and more much more and more much more and more much more and more much more and more much more numerous flavonoid derivatives There is expansion of coronary blood vessels and antiarrhythmic and other effects. Sophora japonica, Sophora japonica tincture on the anesthetized dogs, cats have a significant significant reduction in blood pressure, rutin and its preparations have antihypertensive effect, quercetin can also short-term blood pressure

⑤ on the impact of blood lipids

With cholesterol 30 mg / kg and 6 methyl thiourea 90 mg / kg mixed with food in rats, the formation of hypercholesterolemia, while subcutaneous injection of quercetin 10 mg / kg, can effectively reduce the liver, Aortic and blood cholesterol levels, and increase the stability of cholesterol - protein complexes, experimental atherosclerosis have a preventive and therapeutic effect.

⑥ other effects

Rutin and quercetin in the test tube for some bacteria have antibacterial effect, but also that no antibacterial effect. On the virus, fungi test tube also showed inhibition. Rutin has no inhibitory effect on rat sarcoma -45 and mouse lung adenoma, but Japanese scholars believe that some tumors have an inhibitory effect. Both have an impact on a variety of enzymes. In addition, rutin has a protective effect on X-ray irradiation (the residual rate of mice is higher than that of the control group), and can reduce the mortality rate by using lethal dose of mice. Sophora japonica contains hemagglutinin, agglutination of blood cells. Large doses of Sophora japonica tincture cause some central reflex function to suppress.

It is generally believed that rutin alone does not absorb, so its oral fashion with no therapeutic effect, it is doubtful. Some people think that after oral or can be absorbed.

Concocted Huaihua charcoal: the net Huaihua into the pot, fry until the coke black, storage, a little spray water, remove the dry.

Sex bitter, cool

① "Japan and China Materia Medica": "bitter, flat non-toxic."

② "Southern Yunnan Materia Medica": "taste bitter, cold".

③ "outline": "bitter, cool air."

④ "Materia Medica seeking the original": "bitter salty, cold".

Go through the liver, the large intestine.

① "Materia Medica words": "start Yangming, foot Jueyin by".

② "drug righteousness": "into the lungs, large intestine two".

③ "Materia Medica by solution": "start the lunar lung, hand Shaoyin Heart Sutra".

Functional indications heat, cooling blood, bleeding. Governance intestinal wind blood in the stool, hemorrhoids, hematuria, hemolymph, uterine bleeding, Nvxue, red white diarrhea, wind-hot eyes, ulcer sore. And used to prevent stroke.

① "Japan and China Materia Medica": "rule five hemorrhoids, heartache, eye red, kill the Tibetan insects and heat, cure skin wind, and intestinal bloody blood, red white diarrhea."

② "medical Kai source": "cool big intestine heat".

③ "outline": "fried fragrance chew, governance and the loss of laryngeal paralysis, as well as spit out, bleed at the nose, collapse in the collapse of".

④ "Materia Medica is": "cold large intestine, kill the bugs and worms. Governance ulcer sore sore, acne itching, hemorrhoids, solution Yangmei sore, under the V poison."

⑤ "Medical Lin compile to": "vent lung inverse, diarrhea Firelight, clear anger, Kennedy kidney water."

⑥ "Materia Medica seeking truth": "rule big, hemostasis, tongue bleed at the nose."

⑦ "Materia Medica of the original": "for the cooling blood to medicine. Treatment of gastric pain, kill roundworm."

⑧ "Northeast medicine plantation": "treatment of diabetic retinitis."

Dosage Oral: Jiantang, 2 ~ 5 money; or into the pills, scattered. Topical: Jianshui fumigation or grinding up sprinkle.

Note that the spleen and stomach Deficiency was careful service.

Compound

① treatment of large intestine blood: Sophora japonica, Nepeta ear and other points. For the end, wine clothes a dagger ("experience side")

2 before the Sophora iscocca,

③ governance storm hot under the blood: a pig dirty, washed, control dry, to fry Huaihua end filled with fixed, rice vinegar fried, pot boiled, beat, pill marbles large, dry every serving a pill, hollow, angelica fried ("Forever")

④ governance hemorrhoids bleeding: Huaihua twenty-two, to elm, Atractylodes each one hundred and five money, licorice one or two All fried, research for the fine, every morning and evening before the food served two money. Bleeding (itching itchge Ge Ge Ge Ge Ge Ge because the action is injured, hemorrhoids out of the long-range, such as the line of blood ) Ejiao Decoction ("Du's home copy")

⑤ rule urine urine: Sophora japonica (fried), turmeric (simmer) each one or two. For the end. Each serving two money, light Soup soup. ("Trunk in the secret side")

⑥ treatment of blood shower: Huaihua burned, to fire poison, pestle for the end. Each serving a money, water and wine sent. ("Southern Yunnan Materia Medica")

⑦ governance blood disintegration: Chen Huaihua one or two, paraquat cream half two. For the end. Each serving three or four money, warm wine down; if faint unconscious, then burn red scales hammer wine. ("Good friends pool" Huaihua scattered)

⑧ governance leucorrhea more than: Sophora japonica (fried), oysters (calcined) aliquots. For the end. Each serving three money, take effect. ("Picking party")

⑨ governance Nvxue more than: Sophora japonica, cuttlefish bones and other points. Half a life and a half fried, for the end, blowing nose. ("World Medical Officer")

⑩ governance vomiting more than: how much Sophora japonica. Fire burning, small study, into a little musk. Each serving three money dagger, warm glutinous rice drink down. ("San Ji General recorded" Huai Hong powder)

⑾ governance tongue bleeding more than, said tongue bleed at the nose: Sophora japonica, dried into powder, apply tongue, or fire fried, fire poison, for the end of the application. ("Wonderful recipe, Huaihua dare)

(See fried) two money, fructus aurantium (bran fried) a money. Licorice five points. Shuijianbi. ("Materia Medica")

(2) governance boils swollen poison, all ulcer hair back, do not ask has become, but the pain are all governance: Sophora japonica (micro fried), walnut two twenty, no gray wine clock. Fried more than a thousand boiling, hot clothes. ("Medical summary")

⒁ cure sore: Huaihua two, honeysuckle five money. Wine two bowls of decoction, take sweat. ("Medical enlightenment" Sophora japonica honeysuckle wine)

⒂ governance Yangmei sore, cotton sore and chancre, early sense or poison Sheng difficult to recover: Huaihua Rui (pick the net, do not have to fry), before each meal swallow three money Xu, early in the evening three daily service. If you can not drink, boiling water salt soup can be sent under. ("Jing Yue Quan Shu")

⒃ governance stroke aphrodisiac: fried Huaihua, three more back lying chewing pharynx. ("World Medical Officer")

Clinical application:

① treatment of psoriasis

Take Huaihua fried yellow research into fine powder, each time a money, 2 times a day, after dinner with warm water delivery service. Huaihua can also be made of honey pill oral, the same dose. www.lpjql.com,Clinical observation of 53 cases, 6 cases were cured, significant progress in 22 cases, progress in 19 cases, 6 cases. This drug has a certain side effects of people with gastrointestinal diseases, medication plus vitamin B1, B6 can be alleviated. There are some patients began to have diarrhea, a few days after their own disappearance, so medication should start from a small dose, 2 to 3 days after the addition to the full amount.

② treatment of cervical lymph node tuberculosis

Take 2 pieces of locusta, 1 part of glutinous rice, fried yellow powder, 2 tablespoons of morning fasting service (about 10 grams). During the medication ban sugar. Clinical treatment of more than 30 cases, were cured.

③ treatment Shu boil

With dried Huaihua rice 1 to 2 two, add water 1500 ml of juice, with cotton dipped in local. Juice can be heated repeatedly, 1 day wash 2 to 3 times. While the dregs smashed like mud in the affected area. General medication 1 to 2 days after the local swelling and more.

④ attention to allergic reactions

Reported: 1 case of children, due to mouth with Sophora japonica caused by allergic reactions, fever, facial, neck and limbs skin flushing, surface size ranging from intensive papules, pressurized, itching, tingling, cheek and neck The front area has a diameter of about 0.5 cm round uplift of white blisters and flaky erosion, and a little exudate; patch test positive. The initial treatment with diphenhydramine poor results, after the change to the hydrogenated test of pine and gradually recovered.

Excerpts: "Dictionary of Traditional Chinese Medicine""

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Product basic attributes
Shelf Life: 365 days
Storage: Dry storage, low temperature refrigeration
Organic or inorganic organic

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