Product Code: Bing Lang
Availability: In Stock
$25.00
Ex Tax: $25.00
Chinese Pinyin: Bing Lang,
Aliases: Renpin ("Shanglin Fu"), Binmen (Li Dangzhi "Yaolu"), Binmen medicine candied fruit ("Southern Plants and Trees"), white betel nut ("Medicinal Properties"), olive seeds ("Food Therapy" Materia Medica), Betel Nut ("Waitai"), Xiyingdan (Hou Ningji "Pharmaceutical Biology"), Big belly ("Ling Table Record Different"), Big Belly Betel Nut ("The Sketch Book"), Betel Nut ("Compendium"), Ma Jinnan ("Flower Mirror"), Qingzi ("Chinese Tree Taxonomy"), Pinangyu, Langyu ("Chinese Medicine History").

Name English: Areca catechu L.

Ingredients: Betel nut contains 0.3 to 0.6% of alkaloids, 15% of condensed tannins, 14% of fat and betel nut red pigment. The main alkaloid is arecoline, with a content of 0.1-0.5%; the others are arecoline, desmethyl arecoline, desmethyl arecoline, arecoline, homo arecoline and so on. Raw betel nut contains higher alkaloid content than products.

The endosperm of betel nut contains catechins, anthocyanins and their polymers.

Betel nut contains 14% fatty oil. The constituent fatty acids of betel nut oil are: lauric acid 19.5%, myristic acid 46.2%, palmitic acid 12.7%: stearic acid 1.6%, capric acid 0.3%, oleic acid 6.2%, linoleic acid 5.4%, 0.3% dodecenoic acid, 7.2% tetradecenoic acid. The free amino acids contained in betel nut are more than 15% proline, tyrosine, phenylalanine and arginine are more than 10%, and the non-protein nitrogen content of betel nut is reduced when mature.

Processing and collection: harvest when the fruits are ripe in winter and spring. Pluck the fruit, peel off the skin, take the seeds, and dry.

Identification of medicinal materials: The dried seeds are conical or oblate spherical, 1.5 to 3 cm in height, 2 to 3 cm in diameter at the base, yellowish brown or yellowish brown on the surface, rough, with lighter colored net-shaped concave patterns, and occasionally silver The patchy endocarp is attached. There is a round depressed bead hole in the center of the base, and a light-colored scar-like seed umbilicus beside it. The quality is solid, and the brown seed coat on the outer edge can be seen fold inward in longitudinal section, interlacing with the milky white endosperm, forming a marble-like pattern. There are small embryos inside the basal pores, often brown, withered and shrunken. No gas, astringent and slightly bitter taste. The ones with big weight, firmness and no breakage are better.
    Main products: Guangdong, Yunnan, Taiwan, Guangxi, Fujian. In other countries, Indonesia, India, Sri Lanka, and the Philippines have the most output.

Pharmacological effects:
① Deworming effect
    Arecoline is an effective insect repellent. It has a strong paralyzing effect on pork tapeworms and paralyzes all parts of the worm. For beef tapeworms, it can only completely paralyze the head and immature segments, but has little effect on the middle and posterior segments of the pregnant egg segment. In vitro tests also have a paralyzing effect on pinworms. Arecoline can also be toxic to roundworms but has no effect on hookworms. The decoction of betel nut mixed with realgar, cinnamon, and ferula can be used to prevent schistosomiasis infection in mice, but it is not effective when used together with Hemerocallis root, Coptis chinensis, and cylindrica to treat schistosomiasis in mice.

②Anti-fungal and virus effect
    The water immersion liquid in the test tube has different degrees of inhibition on dermatophytes such as Trichophyton violaceum. Decoctions and water extracts have a certain inhibitory effect on certain strains of influenza virus A, and the antiviral effect may be related to the tannins contained in them.

③The effect on choline receptors
    The effect of arecoline is similar to that of pilocarpine. It can excite M-choline receptors and increase glandular secretion, especially saliva secretion. It can shrink pupils when instilled, and can increase bowel movement, contract bronchial tubes, slow down heart rate, and It can cause vasodilation, drop in blood pressure, and contraction of coronary arteries after application in rabbits. The 1% solution can reduce intraocular pressure when used in light eyes, but the effect lasts for a short time, and it has obvious irritation to the cornea. Due to the increased peristalsis, the paralyzed tapeworm is discharged. It can also excite N-choline receptors, manifested as excitement of skeletal muscle, ganglion and carotid body. It also has a cholinergic effect on the central nervous system. Intravenous injection of a small amount of arecoline in cats can cause cortical awakening. Atropine reduces or blocks this effect.

④Other functions
    Subcutaneous injection of arecoline in mice can inhibit their general activities, and reduce the activity and memory impairment caused by chlorpromazine. It has been proved that betel nut contains carcinogens to humans. People who chew betel nut usually have decreased taste, increased appetite, easily shaken teeth, less diarrhea, less sore throat, and can cure abdominal pain, probably because it contains a lot of tannins. In addition, betel nut eaters have fewer intestinal parasites and less thirst, which may be related to the effect of arecoline.

Concoct:
    Betel nut: pick up impurities, soak in clean water, change the water according to the temperature, until soaked, pick up, slice, and dry. Or take the pure betel nut and smash it as big as beans. Stir-fried betel nut: Put the betel nut slices in the pot, sauté the betel nut until slightly discolored, take it out and let cool. Jiao betel nut: When the betel nut slices are fried with martial fire until brown, spray with water, take it out and let cool.

    ① "Lei Gong Cannon Burning Theory": "If you want to make a betel nut, first scrape off the bottom with a knife, and cut it carefully. Don't put it on fire for fear of ineffectiveness. If you are familiar, it is better not to use it."

    ② "Materia Medica": "Betel nut is used for emergency treatment, but it is weak after fire. Slowly treated with a little stir-fry or boiled in vinegar."

Function and indication:
    Kill insects, break accumulation, get out of breath, and drain water. Cure insect accumulation, food stagnation, abdominal distension and pain, severe diarrhea, malaria, edema, athlete's foot, phlegm addiction, crux.

    ① "Do not record": "The main purpose is to eliminate grains and water, eliminate phlegm addiction; kill three insects, cure inch white."

    ② "Medicinal Properties Theory": "Xuanli five internal organs are stagnant, broken strong, full of qi, and edema. Treating heartache, wind and blood accumulation."

    ③ "Tang Materia Medica": "Mainly treat abdominal distension, smash the powder, and diuretic valley. Apply sores, generate muscles and relieve pain. Burn to ash, mainly muzzle white sores."

    ④ "On athlete's foot": "Cure athlete's foot poisoning, edema."

    ⑤ "Marine Herbal Medicine": "The main qi of ben dolphins, five qi, air-conditioning, and food can not be eliminated."

    ⑥ "Rihuazi Materia Medica": "In addition to all winds, all qi is removed, joints are relieved, nine orifices are benefited, five labors and seven wounds are invigorated, the spleen is invigorated, the spleen is invigorated, the trouble is removed, the crux is broken, and the five qi is reduced."

    ⑦ "Medical Qiyuan": "Heavy after treatment."

    ⑧Wang Haogu: "Treatment of rushing pulse is a disease, and qi adversity is urgent."

    ⑨ "Compendium": "Treatment of severe diarrhea, pain in the abdomen, constipation, constipation, sputum and breathlessness. Treatment of malaria, prevention of malaria."

    ⑩ "Materia Medica Tongxuan": "Relieve malaria and treat hernia."

    ⑾ "Suishiju diet spectrum": "Xuan stagnant breaks the firmness, calms the pain, relieves the pain, clears the intestines and eliminates water, makes fat and sweet poison. And can strengthen the teeth and relieve the breath."

    ⑿ "Modern Practical Chinese Medicine": "Repelling ginger worms and tapeworms, and has the effects of strengthening the stomach, astringent and purging."

Nature and flavor:
    Hard work, warm.

    ① "Do not record": "Taste pungent, warm, non-toxic."

    ② "Compendium": "Bitterness, warm, astringent, non-toxic."

Dosage:
    Oral administration: decoction, 1.5 to 3 yuan (such as single flavor repellent, can be used to 2 to 3 taels); or into pills or powder. External use: decocted and washed or powdered and applied.

Taboo:
    Be cautious when qi is sinking.

    ① "Diet Therapy Materia Medica": "Eat more and have a fever."

    ② "Materia Medica Sutra": "It is forbidden for those with deficiency of qi. Spleen and stomach deficiency, not suitable for those with stagnation; not suitable for those with heart-abdominal pain without knots and non-worm attack; not suitable for those who are not suffering from mountain miasma. Those who belong to the deficiency of both yin and yang and lack of qi, rather than stagnation of the stomach and fullness of the board, are all taboos."

    ③ "Ben Jing Feng Yuan": "If you have diarrhea after diarrhea or malaria, you must not use it."

Storage: Store in a ventilated and dry place to prevent moth.

side effect:
    1. Toxicity: Excessive arecoline causes salivation, vomiting, diuresis, lethargy and convulsions. If it is caused by oral administration, potassium permanganate solution can be used for gastric lavage and atropine injection. 2. Mutagenesis: The LD50 of betel nut decoction to mice ig is 120±24g/kg. The MLD of arecoline given to mice ig is 100mg/kg, the MLD of dogs is 5mg/kg, and the MLD of horses is 1.4mg/kg. The MLD of the ig betel nut bismuth iodine compound in rats was 1g/kg, salivation, diarrhea, rapid breathing, irritability and other symptoms appeared 15min after administration, and died 1.5-2h. Dogs using 0.44mg/kg arecoline hydrobromide ig can cause vomiting and convulsions. Ramesha RA reported that the total water-soluble extract of raw betel nut or betel nut was taken at the doses of 1, 3 and 5 mg/d/head to pregnant rats at 6-15 days. Fetal weight loss, delayed bone maturation, and even stillbirth. Panigrahi GB reported the effect of the total water extract of betel nut and its tannin on the frequency of sister chromosome exchange (SCE) in mouse bone marrow cells. The total water extract of ip betel nut was given to mice at 12.5, 25 or 50mg/g/5 days. The results showed SCE The frequency increased with the increase of the dose, and after continuous injection of 50mg/g/10d, 25mg/g/15d or 50mg/g/15d betel nut total water extract, the frequency of SCE decreased significantly, indicating that the betel nut total water extract was at a low dose It can produce mutagenic effects in a short time. Give mice ip betel nut tannin 50, 100 or 200ug/gx5d, the results showed that the frequency of SCE did not increase significantly, but after continuous injection of 200ug/gx10d, 100ug/gx15d, 200ug/gx15d betel nut tannin, the SCE frequency was significant The increase indicates that betel nut tannin has mutagenic effects under long-term high-dose action. 3. Carcinogenesis-promoting effect: According to Tanaka T et al., after drinking water containing 5ppm of carcinogenic substance 4-nitroquinoline 1-oxide (I) for 16 weeks, rats were given a diet containing 20% ??betel nut for 40 weeks. , The results found that the incidence of tumors on the tongue of the rats added with betel nut was significantly higher than that of the rats who only drank I; the rats were also given po containing 200ppm of another carcinogenic substance N-2-fluorenylacetamide (FAA) After 8 weeks of feed, 16 weeks of feed containing betel nut was added, and the results showed that the number of liver cells in rats that were added betel nut was significantly higher than that of rats that only took FAA. This result indicates that diet betel nut has a cancer-promoting effect on liver cancer induced by 4-nitroquinoline 1-oxide-induced oral cancer N-2-fluorenylacetamide.

Return meridian: stomach; large intestine meridian

Plant form:
    Betel nut
    Trees, 10 to 18 meters high, do not branch, and form obvious rings after the leaves fall off. The leaves are clustered at the tip; pinnately compound leaves, 1.3 to 2 meters long, smooth, leaf shafts 3 prismatic, leaflets lanceolate linear or linear, 30 to 70 cm long, 2.5 to 6 cm wide, narrow base, apex leaflet Healing, there are irregular divisions. The inflorescence is born at the base of the lowest leaf, with large bud-like bracts, obovate, 40 cm long, smooth, multi-branched inflorescence; flowers are unisexual, monoecious; male flowers are small, numerous, sessile , Close to the upper part of branches, usually solitary, rarely opposite, calyx 3, thick and small, petals 3, ovate-oblong, 5-6 mm long, stamens 6, short filaments, anthers base, stylus 3. Filamentous; female flowers are large and few, sessile, inserted on the rachis or branch base, calyx 3, oblong ovoid, 12-15 mm long. The nut is ovoid or oblong, 5-6 cm long, with persistent calyx and petals, red when ripe. It blooms twice a year, the flowering period is from March to August, and the winter flowers do not bear fruit. Fruit period from December to February of the following year.
    Distributed in Guangxi, Yunnan, Fujian, Taiwan, Guangdong and other places.

    The male flower bud (betel nut flower), immature fruit (jujube betel nut), and pericarp (bellied skin) of this plant are also used for medicinal purposes.

Clinical application:
①Treatment of tapeworm disease
    The cure rate of betel nut to pork tapeworm is more than 90%. However, there are also reports of 8 cases and only 4 cases (50%) were cured, which is believed to be related to poor drug quality and improper preparation method. The curative effect of short tapeworms has different reports in the literature: the reported rare cases (1 to 6 cases) were cured; 8 cases were cured and 6 cases (75%); 32 cases had an excretion rate of 37.5%, while stool worms The negative conversion rate of eggs is 82.8%. However, it has been reported that only 3 cases were cured in 14 cases; treatment of 8 cases of children was ineffective. For Schizocephalys latifolia, although individual cases were reported, they were all cured. For beef tapeworm, the curative effect is poor, and the cure rate is generally between 30-50%. If combined with pumpkin seeds, the curative effect can be greatly improved, with a cure rate of 90-95% or more; however, there are also reports of 23 cases of treatment. The results showed that 5 cases were driven out of worm heads, 14 cases were driven out of most worm bodies (no heads were driven out), and 4 cases were invalid. Practice has proved that both betel nut and pumpkin seeds have paralysing effects on tapeworms, but betel nut mainly acts on the first segment and immature segments (i.e., the front segment) of tapeworms, while pumpkin seeds mainly act on the middle and back segments of the pregnant egg segment , The combination of the two can improve the therapeutic effect. Usage: Oral decoction is generally used. The usual amount is 60-100 g, but it is also useful to 120 g or more. Some people believe that increasing the dose beyond the effective dose range will not improve the efficacy. The preparation of the decoction is generally to chop the betel nut, soak it in 300-500ml hot water for several hours, then fry it into about 200ml with warm fire, and take it once in the morning on an empty stomach. Fasting or eating a small amount of liquid diet the night before taking the medicine. After taking the medicine, take 20-30 grams of magnesium sulfate in about half to 2 hours depending on the specific situation. For combined use of pumpkin seeds, first take 80-125 grams of pumpkin seed powder, wait for about half to 2 hours, then take betel nut decoction, and then take magnesium sulfate. The time between the completion of the medication and the deworming varies from half an hour to several hours. Most cured cases only take the medicine once. However, there are a small number of people who need to take the medicine twice or more. According to clinical observations, fresh betel nuts are more effective than those that have been left for a long time; betel nuts soaked in water for several hours before decoction are more effective than immediate decoction; the effect of taking laxatives is better than not taking laxatives; betel nut decoction is injected by duodenal tube The method is more effective than the oral method and has fewer side effects. The combined application of betel nut and pumpkin seeds not only has a significant effect on beef tapeworm, but also improves the effect on short tapeworm. The side effects include nausea, vomiting, abdominal pain and dizziness, palpitation, and also cause hematemesis or intestinal obstruction. Experience believes that keeping quiet after taking the medicine, or taking the decoction cold, or titrating with 2.5% gelatin to remove the tannic acid in the betel nut decoction can reduce side effects such as nausea and vomiting. In addition, the combination of betel nut and adipine can improve the curative effect of beef tapeworm; the combination of betel nut, pumpkin seeds and pomegranate peel also has better effect on pork tapeworm and short tapeworm.

②Treatment of ginger worm disease
    The cure rate ranges from 47.2 to more than 90%. Generally, the worms can be discharged 1 to 3 hours after taking the medicine. The fastest is 15-40 minutes. The preparation and usage of the medicine are generally the same as those for the treatment of tapeworm disease. In addition to the single-flavor decoction, it is also used with ebony and licorice. If it is taken orally with Heichou Yanmo, its curative effect is better than single decoction.
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Product basic attributes
Shelf Life: 365 days
Storage: Dry storage, low temperature refrigeration
Organic or inorganic organic

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